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Abdurrahman Aksoy

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THE RELATIONSHIPS BETWEEN TWO GENERAL ANAESTHETICS AND VARIOUS BLOOD PARAMETERS IN PERSONS UNABLE TO UNDERGO ROUTINE DENTAL TREATMENT WITHOUT ANAESTHESIA

Journal article

A. Koyuturk, M. Yılmaz, A. Aksoy, D. Guvenc, A. Okuyucu, M. Sari, E. Ertaş, M. Sumer
2016
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APA   Click to copy
Koyuturk, A., Yılmaz, M., Aksoy, A., Guvenc, D., Okuyucu, A., Sari, M., … Sumer, M. (2016). THE RELATIONSHIPS BETWEEN TWO GENERAL ANAESTHETICS AND VARIOUS BLOOD PARAMETERS IN PERSONS UNABLE TO UNDERGO ROUTINE DENTAL TREATMENT WITHOUT ANAESTHESIA.

Chicago/Turabian   Click to copy
Koyuturk, A., M. Yılmaz, A. Aksoy, D. Guvenc, A. Okuyucu, M. Sari, E. Ertaş, and M. Sumer. “THE RELATIONSHIPS BETWEEN TWO GENERAL ANAESTHETICS AND VARIOUS BLOOD PARAMETERS IN PERSONS UNABLE TO UNDERGO ROUTINE DENTAL TREATMENT WITHOUT ANAESTHESIA” (2016).

MLA   Click to copy
Koyuturk, A., et al. THE RELATIONSHIPS BETWEEN TWO GENERAL ANAESTHETICS AND VARIOUS BLOOD PARAMETERS IN PERSONS UNABLE TO UNDERGO ROUTINE DENTAL TREATMENT WITHOUT ANAESTHESIA. 2016.

BibTeX   Click to copy 

@article{a2016a,
  title = {THE RELATIONSHIPS BETWEEN TWO GENERAL ANAESTHETICS AND VARIOUS BLOOD PARAMETERS IN PERSONS UNABLE TO UNDERGO ROUTINE DENTAL TREATMENT WITHOUT ANAESTHESIA},
  year = {2016},
  author = {Koyuturk, A. and Yılmaz, M. and Aksoy, A. and Guvenc, D. and Okuyucu, A. and Sari, M. and Ertaş, E. and Sumer, M.}
}

Abstract

This study aimed to investigate the relationships between the blood levels of two general anaesthetics (sevoflurane and propofol), and catecholamines (adrenaline, noradrenaline); serotonin; liver enzymes (alanine transaminase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and gamma-glutamyl transpeptidase (GGT); and lipid peroxidation parameters (catalase, malondialdehyde (MDA) and superoxide dismutase (SOD),  in mentally retarded (n=20), Down Syndrome (n=12) and healthy (n=20) patients unable to undergo routine dental procedures without anaesthesia. Headspace gas chromatography, High Performance Liquid Chromatography (HPLC) and spectrophotometry were used to determine the blood levels of sevoflurane; propofol, catecholamine and serotonin; and liver enzymes and lipid peroxidation parameters, respectively. Although there were some differences between the respective values of the three patient groups before, during and after anaesthesia, no significant correlations were found. Additional studies should be done to further clarify the mechanisms of anaesthesia in difficult-to-treat patients.